The Qinghai-Tibet Plateau is the highest, largest and youngest plateau in the world. Its arid and frigid cli-matic conditions are not suitable for the development of karst landforms based on the principles of climatic geo-morphology. However, the authors have found many micro-forms of karst features in most of places of the plateau. Therefore, the development of the karst micro-landforms on this plateau needs to be investigated. The international standard tablets for examining limestone dissolution rate have been placed in field for 12 years and the experiment reveals that the karst dissolution rate on the plateau is the lowest in the world. With the refer-ence to the CO2 partial pressures that were measured on different elevations, the authors believe that the lower C()2 pressure on the plateau, which is caused by high altitude, is one of the major causes responsible for the lowest dissolution rate. Other causes include arid and frigid conditions. Based on the results from calculation of the dissolution rates and analysis of karst geomorphology, it can be concluded that the active micro-landforms belong to bio-karst features and the appearance of other micro-landforms may be related to the warm periods in Holocene.