Using to the apatite fission track of the three sections in the Shangdan depression, the southeastern margin of the Yin’e basin, the Mesozoic tectonic evolution history in the study area has been studied. The fission track ages of 5 samples range from 129±10 Ma to 159±11 Ma, and the track length range from 125±20 μm to 133±17μm. The track length in these samples is characterized by a wide range, and a unimodal pattern. The results show that the study area has undergone uplift erosion events in the Late Jurassic Early Cretaceous，which have been affected greatly by curtain Ⅲ of the Yanshan movement. Specifically, the depression has experienced a uplifting process at a uplift rate of 40~55m/Ma with decreasing from north to south. It was the major uplifting period of the study area，and the petroleum system was eventually damaged. Since then, to late Cretaceous the Amushan Formation in the study area came into hydrocarbon threshold, which made great contributions to hydrocarbon generation. Combined with the work undertaken in the northern depression belt（Apatite fission track age is 90 113Ma）, it is recognized that there are some different uplifts in the Yin’e basin during the Mesozoic era, and different tectonic sites have been affected significantly by different tectonic movements in varied periods. The results provide a solid basis for tectonic evolution of the Yin’e basin.