Based on the analogy analysis of structural characteristics and the theoretical model of strike-slip duplex，this paper analyzes the development characteristics of strike-slip duplex in the eastern part of Liaodong Bay Depression and discusses its petroleum geological significance combined with practical achievement of hydrocarbon exploration. The analysis indicates that：controlled by the multi-dynamic source geology background caused by the coexistence of strike-slip and extension， Cenozoic tectonic evolution of Liaodong Bay Depression reflects a superposition effect of rift and depression as well as extension and strike-slip. The development of NNE direction faults including Liaozhong 1 fault，Liaozhong 2 fault and Liaodong fault influences uplift-sag distribution of the eastern Liaodong Bay Depression and the stepovers between them lead to the development of strike-slip duplex in study area. Liaodong uplift is a contractional strike-slip duplex due to the fault bends and dextral left-stepped arrangement between Liaodong fault and Liaozhong 2 fault. Liaozhong sag experienced the modification of the late-stage strike-slip on the basis of the early-stage extension and its fault system reflects extensional strike-slip duplex effect resulted by the dextral right-stepped arrangement of Liaozhong 1fault and Liaozhong 2 fault. The stress increasing area of strike-slip duplex contributes to the formation of effective fault traps because of the better lateral sealing and is the favorable zone for the hydrocarbon exploration.