Lithium is one of the strategic resources for the development of high- tech industries in China.Guizhou is rich in bauxite resources and widely distributed aluminiferous rock series. It is found that a large number of lithium resources are associated with bauxite (rock). The results show that the content of Li is high, with a wide variation range (0. 55×10-6~2725. 03×10-6), in the aluminiferous rock series.In the plane, the content of Li is generally high in the northeast (Wuzhengdao metallogenic area), high in the southwest (Xiuwen- Qingzhen metallogenic area), and low in the middle (Bozhou- Wengan metallogenic area). In the profile, Li is mainly concentrated in the dense bauxite (ore) in the upper part of the ore system where it is generally higher than 500×10-6, and generally less than 30×10-6 in the middle- earth bauxite (rock) of the ore system.The continental lacustrine sedimentary environment with warm and humid climate, weathering and strong leachation is conducive not only to the formation of clay minerals mainly composed of kaolinite, but also to the occurrence of Li+ with Al3+, Mg2+, Fe3+ and Fe2+ that are absorbed into the structure between clay mineral layers with migration and enrichment. Li was positively correlated with Al2O3 content. In the secondary transformation stage after diagenesis and mineralization, paleomagnetic survey and CIA showed that the oxidation environment was hot and humid. With the enhancement of weathering, desilication and aluminum enrichment, a large amount of Li and SiO2 are lost, showing a negative correlation between Li and Al2O3 content and a positive correlation between Li and SiO2 content. The enrichment of Li is closely related to geochemical properties, paleosedimentary environment and epigenetic transformation. Li is mainly derived from the underlying strata with high background, which is consistent with the parent rock of bauxite mineralization. Part of Li may also be derived from the overlying strata rich in Li. The enrichment characteristics of Li in aluminous rock series show that lithium has good prospecting potential.