The Central China Orogenic Belt is a compound orogenic belt formed by the complex amalgamation of many Laurasia- associated northern blocks, Gondwana- associated southern blocks, and many transitional micro- blocks in- between. It is a tectonic combination zone where the main body of mainland China has been assembled. The Central China Orogenic Belt includes, from west to east, the Kunlun Orogen,Qilian Orogen, and Qinling- Dabie Orogen, and preserves abundant information on the Paleozoic- Early Mesozoic orogenic processes of North China, South China, Qaidam, Tarim, and Qiangtang Blocks. It offers a critical window to study the tectonic evolution from Proto- Tethys to Paleo- Tethys Oceans in the East Tethys tectonic domain. This contribution reviews the geological, geochemical and high- precision geochronology dataset from the Central China Orogenic Belt, and draws the following main conclusions: ① Before 550 Ma, many large- small- sized blocks were isolated and scattered in the Proto- Tethys Ocean; ② During 541~485 Ma, all branches of the Proto- Tethys Ocean began to subduct; ③ During 485~444 Ma, the Proto- Tethys Ocean continued to subduct, resulting in the opening of the Erlangping back- arc basin in the Qinling area and the Qimantagh back- arc basin in the Kunlun area; ④ During 444~420 Ma , the Paleo- Tethys North Qilian, South Qilian, and Shangdan Oceans and Qimantagh back- arc basin were closed; ⑤ At 420~300 Ma, the Paleo- Tethys Ocean inherited the Proto- Tethys Ocean in the Kunlun area, and the Paleo- Tethys Mianlue Ocean gradually spread; ⑥ During 300~250 Ma, the Kunlun Ocean subducted and retreated from the Aqikekulehu- Kunzhong suture to the Muztagh- Buqingshan- Anemaqen suture; ⑦ During 250~200 Ma, the Proto- and Paleo- Tethys Kunlun Ocean and the Paleo- Tethys Mianlue Ocean were closed; ⑧ Since 200 Ma, the Central China Orogenic Belt transitioned into intracontinental orogeny.