As one of the most important members of the metal stable isotope family, zinc isotopes have attracted quite a lot of attention by international scientific community since the last century. In the 21st century, with the development of multi.collector inductively coupled plasma.mass spectrometry (MC-ICP-MS), the applications of zinc isotope have been greatly expanded and deepened in the Earth and planetary science. Here we provide a relatively detailed overview of research on zinc isotopes, including the reference materials and analytical methods of zinc isotopes, the zinc isotope compositions of the main reservoirs in nature, the behavior and fractionation mechanisms of zinc isotopes in different geological processes, and recent advances on zinc isotopes in the four fields of Earth science: ① tracing the deep carbon cycle, recycled oceanic materials and the origin of compositional transition of alkaline basalts; ② tracing the sources of ore.forming material, microbial mineralization, and indicating mineral exploration; ③ unrevealing the origin and evolution of the moon; ④ indicating the primary productivity, biogeochemical processes, and the mechanism of the mass extinction at the end of Permian. In the future, with the development of zinc isotope microarea in situ analysis technology, zinc isotopes will be widely used in geosciences, especially in ore deposits, and biomedical sciences.