Magmatic activities and metamorphism related to Paleozoic oceanic subduction and collisional orogeny have been widely developed in North Qinling tectonic belt, but the Paleozoic hydrothermal vein-type metal deposits are rarely reported in the North Qinling. The Yindonggou silver-gold-polymetallic deposit is a medium-size deposit in the eastern part of North Qinling. This paper presents the LA-MC-ICP-MS zircon U-Pb age of the ore bearing quartz veins and biotite monzogranite host rock to determine the formation age of the deposit and constrain the metallogenic dynamic setting. It indicated that the biotite monzogranite and ore-bearing quartz vein were emplaced at 431.4±2.1 Ma and 419.4±5.9 Ma, respectively. Based on the study of zircon petrography, mineral and fluid inclusions in zircon, and trace elements of zircon, we constrained that the metallogenic age of the deposit is 419.4 Ma. Considering previous research results, we proposed that the Yindonggou silver-gold-polymetallic deposit is an orogenic-type deposit. The mineralization is closely related to the post-collisional metamorphism process at about 420 Ma. The ore-forming fluids were dominantly derived from the metamorphic dehydration of the strata, while the ore-forming materials were mainly sourced from both the Qinling Group and the Erlangping Group.