The REE biogeochemistry of the weathering crust of acid rocks in south China was reviewed. Then effects of some amino acids on the dissolution of REE from g ranites as well as on the downward migration of REE in weathering profiles of th e granites were studied. The results show that most of the studied amino acids can accelerate the dissolution and migration of REE in the weathering profiles. The impoverishment of REE orebodies in the weathering crust and its environment al pollution were also studied at the end of the paper.