Seeing the disorder of the division standards of engineering geological strata, this situation is not conducive to the communication and socialization of engineering geological data. In order to improve the universal of engineering geological data, taking the engineering geological 100m strata as the object combined with 11 a 1∶50000 standard sheet engineering geological survey work in the study area. Considering sedimentary age, sedimentary environment, soil structure characteristics and physical and mechanical parameters, the engineering geological 100m strata were divided into 7 engineering geology strata and 21 layers, and were given the basic sequence stratigraphic structure and coding. Through the establishment of engineering geological layer group, the corresponding relationship is found out between drilling and soil layer of large area engineering. It makes the contrast analysis of regional stratigraphic data potentially. It helps to geological model of generalized and seizes the engineering geological problems. It analysed the group rationality of engineering geological layer through parameters of the discrete analysis, geological profile drawing and the establishment of threedimensional model. It is confirmed that the result of layer group division is reasonable and correct. Through the establishment of the engineering geological strata groups, it found out the two sensitive preferred strata and four dominant bearing strata. The results has a certain guiding significance to engineering investigation, urban planning and construction project location demonstration in the north of the Yangtze river delta region.