Uzbekistan is one of the region with the greatest exploration potential of uranium resources in Central Asia. Therefore, understanding and analyzing the basic situation of uranium resources and the investment environment of uranium resources in Uzbekistan can provide basic and information support for the long- term sustainable development of natural in China. Based on the investigation of authoritative wind stations and reports and atracking of the latest information, this paper provides an in- depth and comprehensive analysis on the resources distribution, current situation of exploration and development, and foreign cooperation policies, and puts forward a suggestion :“we need pay attention to the mining policy of Uzbekistan in real- time, and establish mutually benefucial cooperation relations with its uranium resources and seek project coorperation development using advanced nuclear industry technology.” The paper is a comprehensive paper on the distribution of uranium resources in Uzbekistan and the analysis of the current development situation, which provides important basis data and information support for China’s natural uranium enterprises to “going- out”.